REACTION AND DIFFUSION MECHANISMS IN MAMMALIAN CELL VIA IN SILICO MODELING

Authors

  • S. Zahid Department of Mathematics, University of Engineering and Technology, Lahore, Pakistan
  • S. Khalid Department of Mathematics, University of Engineering and Technology, Lahore, Pakistan
  • Q. A. Chaudhry Department of Mathematics, University of Engineering and Technology, Lahore, Pakistan
  • S. Riaz Department of Mathematics, University of Engineering and Technology, Lahore, Pakistan
  • A. Shuaib Department of Physics, University of Engineering and Technology, Lahore, Pakistan
  • M. Gull Department of Mathematics, University of Sagodha, Lahore Campus, Pakistan
  • N. Abid Department of Mathematics, University of Engineering and Technology, Lahore, Pakistan

Abstract

Due to complex structure of cell, mathematical modeling of the diffusion and reaction of toxic compounds in mammalian cell is becoming more and more interesting and predominating. Polycyclic aromatic hydrocarbons (PAHs) are highly lipophilic, react with DNA and may cause many diseases like cancer and tumor etc. In mammalian cell, cytoplasm has various tiny membrane layers, i. e., lipid and water. We have constructed a mathematical structure where cytoplasm is consider as a cumulation of seperate sub-domain. To check the validity of incipient non-homogenized model, numerical results were compared with homogenized model which are very close to each other.

Downloads

Additional Files

Published

2015-04-13

How to Cite

Zahid, S., Khalid, S., Chaudhry, Q. A., Riaz, S., Shuaib, A., Gull, M., & Abid, N. (2015). REACTION AND DIFFUSION MECHANISMS IN MAMMALIAN CELL VIA IN SILICO MODELING. Journal of the Pakistan Institute of Chemical Engineers, 43(1), 105–109. Retrieved from http://piche.org.pk/journal/index.php/jpiche/article/view/234

Issue

Vol. 43 No. 1 (2015): JOURNAL OF THE PAKISTAN INSTITUTE OF CHEMICAL ENGINEERS (JPIChE)

Section

Articles

License

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).