Optimization of Extraction Process for Licorice Commercial Extract Using Single Pot Solvent Extraction Unit
Abstract
Licorice is the root of Glycyrrhiza uralensis Fisch, botanical herb that has been widely used since many years. Extensive studies have reported its clinical value which includes anti-inflammatory, immunomodulatory, anti-cancer, anti-ulcerative, anti-viral and anti-microbial properties. Licorice powder was used a a raw material and water plus ethanol was used as a solvent. The extraction process of licorice extract from powder was studied with a single pot solvent extraction method in order to optimize the Extraction process. The effect of three variables i.e. extraction time, extraction number and ratio of solvent to feed on the extraction yield, extraction value and brix value was investigated. The optimum extraction time was found to be 6h for first and second stage and 4h for third stage. Optimum values of yield, extractive value and brix value were obtained when the extraction unit was operated on third extraction stage. Similarly the optimum solvent to feed ratio found was 40:10, 40:10 and 60:10 for the 1st stage, 2nd stage and 3rd stage respectively. The extraction unit may be operated on these values to get optimum production of Licorice extract from licorice powder.
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